Factors characterizing Staphylococcus epidermidis invasiveness determined by comparative genomics.
نویسندگان
چکیده
Virulence mechanisms of the leading nosocomial pathogen Staphylococcus epidermidis are poorly understood. We used microarray-based genome-wide comparison of clinical and commensal S. epidermidis strains to identify putative virulence determinants. Our study revealed high genetic variability of the S. epidermidis genome, new markers for invasiveness of S. epidermidis, and potential targets for drug development against S. epidermidis infections.
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عنوان ژورنال:
- Infection and immunity
دوره 73 3 شماره
صفحات -
تاریخ انتشار 2005